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Missing doses or irregular administration patterns may prevent steady therapeutic levels, reducing appetite suppression

Extrapolating from B12 supplementation trials of non-vegans to determine the needs of vegans is complicated by the fact that a high percentage of any small dose of B12 is absorbed and omnivores are normally receiving numerous small doses throughout the day

Changes in stool frequency following chicory inulin consumption, and effects on stool consistency, quality of life and composition of gut microbiota

A better understanding of trial enrollment and results reported for specific demographic populations is likely to accelerate scientific progress and ultimately lead to more effective treatment options for all patients