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By the end of the study, 44 participants had completed the trial

Research endpoints: cellular NAD+ quantification

Barzanti V, Battino M, Baracca A, Cavazzoni M, Cocchi M, Noble R, Maranesi M, Tur chetto E, Lenaz G: The effect of dietary lipid changes on the fatty acid composition and function of liver, heart and brain mitochondria in the rat at different ages

Clinical signs that might suggest compromised medication include unexpected loss of appetite suppression, return of cravings, or weight loss plateau that cannot be explained by other factors such as dietary changes or increased caloric intake