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AC has been reported to have nephroprotective effects by acting against many aspects of DKD pathogenesis and progression

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Changes of flux in any one of these pathways will influence pyruvate concentration and thus directly affect lactate concentration as the two are maintained close to thermodynamic equilibrium

The detailed mechanism of cellular copper delivery from GHK-Cu whether the complex is taken up intact, whether copper is transferred at the cell surface, and how the copper is subsequently routed within the cell has been characterized in some detail in the published research but is not fully resolved at the level of all intermediate steps