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doi: 10.1186/1471-2091-8-8 [DOI] [PMC free article] [PubMed] [Google Scholar] 208.Shi C, Zhou Z, Chi X, et al

[5] Nonmelanocytic tumors such as subungual linear keratosis, [8] verruca vulgaris, subungual fibrous histiocytoma, basal cell carcinoma, myxoid pseudocyst, [9] Bowen's disease, [10] and onychomatricoma have also been shown to induce melanocytic activation, which leads to longitudinal melanonychia

Once you've successfully tried low-concentration retinols in the 0.25-0.5% range, you can work your way up to higher percentages for more advanced treatment

Yet this effect is more pronounced and common with Acetyl-L-Carnitine