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However, the observed phenotype in these mice was again not a simple ramification of mucosal barrier deregulation, but was the result of a conglomerate of defects in epithelial homeostasis, including epithelial cell apoptosis and barrier function irregularities

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While BPC-157 has shown some interesting results in laboratory rodent studies for tendon and soft tissue healing, there are zero peer-reviewed, long-term clinical trials on its safety or efficacy in dogs, she says