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No Significant Increase in Heart Failure Risk: Concerns regarding an increase in heart failure with saxagliptin, and to a lesser extent alogliptin, resulted in no use or cautious use of these agents in patients with cardiac backgrounds

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Therefore, in order to mitigate patient risk, pre-vaccine serological screening is crucial to ensure that only seropositive patients are vaccinated

TTR-V30M amyloidosis is associated with inflammation, linking the disease indirectly to oxidative stress Although oxidative stress in vivo may arise through several different routes, it is frequently linked to inflammation