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The reduction of cardiovascular events is not only related to anti-diabetic properties, but also to pleotropic effects leading to the reduction of the residual cardiovascular risk, that has been defined as the risk of progression of CV events (MACE or HF) that remains after the optimal glycaemic control in T2DM patients, and it seems to be related to meta-inflammation, defined as a low-grade chronic and sterile inflammatory status

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However, many inflammatory factors and oxidative stress, which were prevalent within the microenvironment of liver fibrosis, could significantly impact the activity and stability of rec-ECM1

Lu J, Ren D, Wang J, Sanada H, Egashira Y (2010) Protection by dietary spirulina platensis against d-galactosamine- and acetaminophen-induced liver injuries