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Fecal excretion of total carnitine was less than 1% of the administered dose.10 After attainment of steady state following 4 days of oral administration of levocarnitine tablets (1980 mg q12h) or oral solution (2000 mg q12h) to 15 healthy male volunteers, the mean urinary excretion of levocarnitine during a single dosing interval (12h) was about 9% of the orally administered dose (uncorrected for endogenous urinary excretion)

Rather, the clinical benefits from lipid lowering are probably due to decreases in macrophage accumulation in atherosclerotic lesions and inhibition of MMP production by activated macrophages (99)

Archived from the original on October 25, 2012

Arch Toxicol 95:27692784