Oral semaglutide may even lead to less nausea and vomiting than once-weekly dulaglutide and once-daily lixisenatide (two less common GLP-1 injectable medications), though its nausea profile is similar to that of injectable semaglutide
Diabetes 64(3):819827 Coskun T, Sloop KW, Loghin C, Alsina-Fernandez J, Urva S, Bokvist KB et al (2018) LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: from discovery to clinical proof of concept
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However, unlike Ozempic and Wegovys active ingredient, tirzepatide works on a second hormone receptor, GIP (glucose-dependent insulinotropic polypeptide), which some studies suggest is more effective than semaglutide for blood sugar control and weight loss