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One last thing worth knowing for context: Octinoxate has been the subject of ongoing review in Europe where the Scientific Committee on Consumer Safety's (SCCS) 2025 final opinion is that this ingredient is an endocrine-active substance

We appreciate the support of Amanda Namchuk, Travis Hodges, Bonnie Lee, and Natascha Diekow, who contributed to the experiment endpoints and tissue collections

The insula in nicotine use disorder: Functional neuroimaging and implications for neuromodulation

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