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Clinical studies show 20 to 30 percent improvement in skin firmness after 12 weeks, with significant gains occurring in this middle period

Beyond gastrointestinal effects, clinical data and class-level evidence from licensed incretin agents (semaglutide, tirzepatide) have flagged concerns regarding: Heart rate elevation: Increases in resting heart rate are a recognised class effect of GLP-1 receptor agonists, documented in the SmPCs for semaglutide (Wegovy) and tirzepatide (Mounjaro)

In this episode of The Diary Of A CEO with Steven Bartlett, Anna Lembke explores the critical role of dopamine in driving motivation and the brain's reward pathway