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Taking into account that SGLT-2i and GLP-1RA are recommended as therapeutic alternatives by many clinical guidelines, usually as second-line treatments after first-line metformin, new users of SGLT-2i appear to be a suitable active comparator group

The most common adverse effects are mild gastrointestinal symptoms (nausea, vomiting, diarrhea) that typically occur at rates similar to placebo in controlled trials

During the same period a year ago, the company brought in $316 million in revenue