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10.1007/s11596-018-1989-8 214 YuS.LiuF.WangC.ZhangJ.ZhuA.ZouL.et al (2018)

It is common to gain some of the weight back after you stop taking the weight loss drug, especially without maintaining a healthy lifestyle

Conclusion This study suggests that innate and adaptive immune cells have distinct distribution profiles in the salivary glandular tissues of patients with pSS and highlights mitochondrial metabolic pathways that may contribute to disease progression

Consider Periodic Reassessment If constipation remains severe and quality-of-life-impairing despite all interventions, periodic reassessment with your provider makes sense