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Furthermore, potential predictors of affective switching with antidepressants may include bipolar I disorder (versus bipolar II), mixed features during depression, tricyclics and partly dual-action inhibitors versus modern antidepressants [26], rapid cycling and possibly a history of drug abuse, especially stimulant abuse [27]

Antioxidants such as vitamins C and E, green tea, CoQ10, and resveratrol mop up free radicals, and glutathione is the most powerful antioxidant of them all

Special thanks to BioRender for their technical support in drawing Figures 1 ( Conflict of interest The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

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