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In a randomized, placebo-controlled trial of 20 obese, insulin-resistant adults, 4 weeks of TUDCA (1,750mg/day) improved hepatic and muscle insulin sensitivity but did not reduce liver fat.6 There are no completed human trials showing TUDCA improves NAFLD histology or imaging

The functional relevance of this metabolic shift was confirmed by pharmacological inhibition of mitochondrial respiration, which abolished the survival benefit conferred by cholesterol supplementation, underscoring the central role of mitochondrial metabolism in mediating host protection

Savineau, Jean-Pierre, et al

Influye la alimentacin en la eficacia