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Immediate impacts Increased market competition Potential price reduction Broader access to treatments New opportunities for pharmaceutical players From an intellectual property perspective, this case highlights the strategic importance of patent lifecycle management

Most US compounding pharmacies source from: Bachem (Switzerland): patent-cleared peptide manufacturer Cayman Chemical (Michigan): US-based research chemical supplier with pharma division Chinese API houses registered with the FDA, including Sinopep and several others The FDA requires US compounders to use API from facilities that are FDA-registered (drug master file on record)

TGF- is widely recognized for its potent ability to induce the epithelialmesenchymal transition in various cell types, including hepatocytes