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Moreover, a similar pretreatment reduced LPS-stimulated production of proinflammatory cytokines in BV-2 cells

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Wooten SV, Wang F, Roth ME, Liu G, Livingston JA, Amini B, Gilchrist SC, Hildebrandt M , Kleinerman ES

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By activating FOXO, SIRT1 increases the expression of antioxidant enzymes like MnSOD and CAT, which counteract the formation of ROS [126,127]

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