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We have previously shown that schistosome redox defenses are limited, and that as such they can be disrupted pharmacologically leading to worm death in vitro and in vivo 15

Excessive doses and overdose [edit] Symptoms of ethanol overdose may include nausea, vomiting, CNS depression, coma, acute respiratory failure, or death

Thus, the antitumor effect of oltipraz requires Nrf2 function