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PIT is particularly effective for neuropathic pain, complex regional pain syndrome, and patients with widespread chronic pain that has not responded to conventional treatment

[48] Vegan advocacy organizations, among others, recommend that every vegan consume B 12 from either fortified foods or supplements

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[14] Some healthcare providers may also use biotin injections in patients who have normal biotin levels but are seeking potential benefits for hair and nail health, although the evidence for efficacy in such cases is limited