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FTO , GLP1R (the GLP-1 receptor gene and direct drug target), MC4R (central to satiety), and TCF7L2 (linked to glucose homeostasis and GLP-1 secretion) map the metabolic terrain any GLP-1 compound works within

In a large Swedish study published in JAMA Psychiatry in November 2024, scientists found that people who were taking the GLP-1 drugs semaglutide or liraglutide were less likely to be hospitalized for AUD

a multilayered approach that concurrently inhibits synovial inflammation, modulates immunometabolic processes, and safeguards chondrocytes from ferroptosis-induced injury may yield more robust clinical benefits

Li, K.B