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However, due to its metabolic instability and poor pharmacokinetics, Fer-1has been used only as a research tool to study various iron-related processes and cannot serve as a clinical drug

Liposomal formulations have proven to be significantly more effective with the same dosage

Administered subcutaneously, its injectable form is rapidly absorbed and distributed to metabolically active tissues, where it specifically binds and inhibits NNMT catalytic activity without interfering with other enzymes in the nicotinamide pathway or NAD+ synthesis

10.1007/s002539900295 Appl