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Source: Coskun et al., The Lancet 2022 Phase 2 Results Phase 2 -- Obesity (NEJM 2023) NCT04881760 | Published: New England Journal of Medicine , 2023 (Jastreboff AM, et al.) This was the landmark Phase 2 trial that put retatrutide on the map

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The results were impressive, with a 2.53x increase in free testosterone and a 2.15x increase in total testosterone, and other biomarkers maintaining evidence of good health