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also demonstrated that Asn levels are increased in activated CD8 + T cells and bind to the SRC family tyrosine kinase LCK, assisting in the phosphorylation of LCK at Tyr394 and 505, enhancing LCK activity and T-cell receptor signaling

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Clinically BPH is manifested as lower urinary tract symptoms (LUTS) and consisting of voiding and storage symptoms such as slow urinary stream, splitting or spraying of urinary stream, recurrent urinary stream, straining to void and terminal dribbling, hesitancy, urgency, increased frequency, and incontinence