glp-1 psychiatric side effects The expanding role of receptor agonists: a narrative review of current evidence and future directions Psychotropic effects of GLP-1R agonists

This finding suggests potential benefits for diabetes prevention or early intervention

GIP, or glucose-dependent insulinotropic polypeptide, is another incretin pathway involved in nutrient response

They often lead to water loss rather than meaningful fat reduction and can cause electrolyte imbalances when overused

Therefore, while efforts undoubtedly need to be intensified towards preventing the onset of the disease and making lifestyle modifications (a fundamental aspect of the therapy for every patient with T2DM), it is clear, as indicated by the most recent guidelines [78], that the pharmacological approach should focus on timely treatment that leaves no room for therapeutic inertia and employs medications that are as effective as possible in both metabolic control and the prevention of chronic complications