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In patients with obesity, significant weight reduction achieved with GLP-1 therapy has been associated with improvements in sex hormone-binding globulin (SHBG) levels, reductions in free testosterone in women with hyperandrogenism, and normalization of menstrual cycles in some individuals with polycystic ovary syndrome (PCOS)

The patients who achieve the best long-term outcomes are usually the ones who combine treatment with healthy eating, regular activity, and realistic expectations. Karla K

Diets, polymorphisms of methylenetetrahydrofolate reductase, and the susceptibility of colon cancer and rectal cancer

A 2018 meta-analysis published in Diabetes Care pooled GLP-1 agonist trial data and found no significant increase in pancreatitis risk (relative risk 0.93 to 95% CI 0.65-1.34)