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Multiple early-phase clinical programs have evaluated agents modulating these mechanisms, such as CCR2/CCL2 blockade (emapaticap pegol, CCX140-B) (Zhou et al., 2025b), IL-6 neutralization (ziltivekimab), and anti-fibrotic candidates like pirfenidone or ASK1 inhibition (selonsertib) (Petrovic et al., 2025) (Figure 6)

J Gerontol A Biol Sci Med Sci 50A (11), 1116

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The Boots Vitamin B12 Service is designed to assist those who might have nutritional gaps in their diet, like those following a strict plant-based or vegetarian diet, as vitamin B12 is typically found in meat, fish and dairy products