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(4) mGPDH in the regulation of ferroptosis G3P metabolism supports ferroptosis defense in disease contexts In the first study identifying mGPDH as a ferroptosis regulator, metabolomic analyses revealed that treatment of cancer cells with GPX4 inhibitors led to a marked depletion of intracellular glycerol3phosphate (G3P) 99

[55] [56] [57] Superoxide dismutase is not expressed in neural crest cells in the developing fetus

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338,339 High expression of miR-24-3p, miR-199a-3p and miR-29a-3p has been shown to improve the intestinal barrier in UC, thereby alleviating disease progression