You mentioned gut, and I think its probably worth noting that, you know, the largest concentration of diamine oxidase is in the lining of the gut, meaning if you have any digestive issues, gastrointestinal inflammation, you immediately lose that, you know, frontline histamine-metabolizing layer, which also then leaves you more vulnerable to reactions to dietary histamines, because its DAO that would normally take care of those for you
Studies have demonstrated not only visceral fat loss, increased skeletal muscle, and improved body composition,9 17 18 but also elevated secretions of growth hormone and IGF-1.19 But when the body experiences changes in one area of function, it can have a cascading effect on other areas as well
If you still feel a little tender, applying a cold pack to the site for about 15 minutes can also provide quick relief from pain and swelling
It can help the overall look of uneven tone, but stubborn spots often need a broader plan: sunscreen, targeted brighteners (like niacinamide or azelaic acid), and time