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The use of oral semaglutide incurred an additional cost of $742.88, $5,006.73, and $3,706.50, resulting in ICERs of $33,041.06/QALY, $21668.64/QALY, and $34,061.37/QALY, when compared to patients receiving liraglutide, lixisenatide and dulaglutide, respectively

In adults and older children, the total volume used should also stay within safe limits animal studies suggest up to about 30 mL (the full vial) can be given to an adult without benzyl-alcohol toxicity, but one should still use only the amount needed and discard the rest if sterility is lost