Sex differences in human adipose tissues - the biology of pear shape
A., Dvorkin, E., Homel, P., Malamud, S., Culliney, B., Lapin, J., & Esteban-Cruciani, N
When those muscles are then surrounded by fat, it significantly increases the risk of complications like: Diabetes Heart disease Liver complications such as fatty liver disease High blood pressure Stroke Developing certain types of cancer These risks and the effects of belly fat can significantly hinder a patients life and well-being
This study used: National register infrastructure across multiple countries Active comparators (DPP-4 inhibitors) Quantified upper confidence bounds to show maximum plausible effect size International Multisite Cohort (Thyroid Journal) Analysis of six population-based databases found no evidence of increased thyroid cancer risk with GLP-1 RA use over 1.8-3.0 years follow-up