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Translation to humans remains uncertain due to physiological differences

Intestinal diseases such as Crohns and celiac disease could cause problems

83% of peptide-aware Americans want the FDA to make peptides more accessible Days before an FDA advisory committee meets to consider whether seven widely used peptides BPC-157, TB-500, KPV, MOTS-c, Emideltide (DSIP), Semax, and Epitalon should become eligible for compounding, a new survey suggests thats what Americans want

Drug-induced, reversible channelopathies Various drugs can phenocopy ECG features and arrhythmias of genetic channelopathies by interacting with different cardiac ion channels, causing for example acquired LQTS and BrS-particularly in patients harbouring single-nucleotide polymorphism variants or even silent disease-causing mutations [85]