does tirzepatide cause dry eyes & The Relationship Between Obesity & Skin Issues Vision loss: GLP-1 drugs like

doi: 10.3389/fmicb.2021.661195 106 BangKParkSYooJYChoS

PubMed Exocrine glands in the submucosa of the proximal duodenum secrete alkaline fluid containing mucus to protect the intestinal mucosa from acidic stomach contents

While there are still many questions about TCF7L2 left unanswered, it has been shown that TCF7L2 is essential to the production of proglucagon via the intestinal cells (not the glucagon produced in the alpha cells of the pancreas).[ref] Genetic variants in TCF7L2 are associated with impaired glucose stimulation of insulin secretion and GLP-1.[ref] GLP1R (glucagon-like peptide 1 receptor) receives the signal from GLP-1, and variants in GLP1R have associations with altered BMI, weight, and insulin resistance

By neutralising free radicals, it helps slow down the visible signs of ageing such as wrinkles and fine lines