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Dietary Restrictions Those who follow strict vegetarian or vegan diets may not get enough vitamin B12, as it is primarily found in animal products

Interactions There are no documented risks of drug or supplement interaction with the standard vitamin B12 injections dosage and frequency

Human data on the compound is sparse

Further mechanistic studies showed that NNMTi increases intracellular NAD levels and activates the SIRT1 pathway by inhibiting NNMT, thereby suppressing the transcription of adipogenic genes and preventing the maturation of preadipocytes.This research provides a new perspective for understanding the molecular mechanism of adipocyte differentiation, confirms the key role of NNMTi in regulating adipogenesis, and lays a foundation for subsequent obesity intervention studies