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28 Additionally, a 16-week trial of supplementation with GlyNAC (which boosts glutathione levels) in older adults improvedand in some cases reversedmultiple hallmarks of aging, including inflammation, mitochondrial dysfunction, and oxidative stress

doi: 10.1016/s0167-4889(03)00043-0

Peripheral artery disease pain symptoms : A study found that an intravenous glutathione supplement helped ease pain in people who had decreased blood flow to their legs due to vascular disease

Instead, they are more commonly applied to generate spheroids formed through the assembly of various cell types, a practice widely used in tumor research, but also with some applications in modeling cardiac tissue envisioning the potential use in treating CVDs [248,249,250,251]