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Cardiovascular Risk Markers TRIUMPH-4 also assessed a panel of cardiometabolic biomarkers, and the results were broadly favorable across the board: Non-HDL cholesterol significant reductions, indicating improved atherogenic lipid burden Triglycerides meaningful decreases, consistent with the known effects of GLP-1 and GIP receptor activation on lipid metabolism High-sensitivity C-reactive protein (hsCRP) substantial reductions, reflecting decreased systemic inflammation

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Oxygen consumption has long been attributed to hydroquinone auto-oxidation and the formation of H 2 O 2 and O 2 . 3,5,22

While delayed gastric emptying is great for weight loss and blood sugar control, it can put pressure on the lower esophageal sphincter (LES)