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The 2025 systematic review in orthopaedic sports medicine looked at 35 animal studies and found no lethal dose across multiple administration routes and a wide dosing range (6 g/kg to 20 mg/kg)

Usage schedule and dosage may vary depending on body type, workout routines, fitness goals, and wellness requirements

3 Clinical trial of flavonoids in liver diseases This is supported by Tehrani et al.s work demonstrating that soy isoflavones could significantly reduce triglyceride, low density lipoprotein, total cholesterol, waist circumference and hip circumference in NAFLD patients in a randomized clinical trial involving 50 patients with NAFLD (Neshatbini Tehrani et al., 2024)

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