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The patient did not miss any treatments and tolerated the expected side effects of treatment, including grade 1 dermatitis of the right neck and right cheek, along with hair loss in the treatment field

(98) Accordingly, future trials should enroll truly deficient, high-risk patients

It is believed that five distinct melanocortin receptors exist, labeled melanocortin 1 receptors (MC1Rs) through melanocortin 5 receptors (MC5Rs), each associated with specific potential roles: (2,3) MC1R: This receptor is thought to reside in melanocytes - a kind of skin cell that may influence skin and hair pigmentation, potentially by promoting melanin synthesis