Reported Effects Reduced dependence on intravenous nutrition the pivotal result: In the 24-week STEPS trial (n=86), 63% of teduglutide patients vs 30% on placebo achieved at least a 20% reduction in weekly parenteral support volume (p=0.002), a mean reduction of 4.4 L/week vs 2.3 L/week [2]
Other ingredients: citric acid, potassium sorbate, purified water, sucralose, phosphoric acid, natural & artificial flavor, dl-malic acid, acesulfame potassium, sodium benzoate.
Common side effects include injection site reactions (pain, redness, swelling), gastrointestinal symptoms, and allergic reactions
Different formulations within this class have dramatically different half-lives, ranging from hours to days, which directly impacts their dosing frequency and elimination timeline