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Key finding: Ipamorelin increased serum IGF-1 by 52%, hepatic IGF-1 mRNA expression 3.8-fold, skeletal muscle IGF-1 expression 2.9-fold

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Systemic Side Effects Gastrointestinal Side Effects The most commonly reported side effects of GLP-1 RAs are gastrointestinal, including nausea, vomiting, diarrhea, constipation, abdominal pain, and dyspepsia [113,114,115]

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