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ROS can reduce endothelial barrier function, facilitating lipoprotein deposition and oxidative modification of low-density lipoprotein (LDL) particles in the vessel wall [104]
In fact, in cells undergoing lethal oxidative stress, cellular protein-SSG levels show a positive relationship with GSSG levels 39
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Preclinical and small human studies suggest it may influence telomerase activity and circadian and melatonin regulation
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