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The approval was granted under the FDAs National Priority Voucher programme, making it the fastest new molecular entity approval since 2002

This safety profile makes it ideal for patients with type 2 diabetes or insulin resistance

Common examples include verification of instrument response during LC-MS method development, evaluation of matrix effects and extraction recovery during sample-prep validation, confirmation of container-compatibility behavior over defined time windows, and standardized dilution-chain execution across replicate assay plates

If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution