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7.6 Reframing complexity as translational opportunity Collectively, the neuroendocrine and immunemetabolic peptide systems reviewed in this section challenge the assumption that therapeutic targets must be narrowly defined, peripherally restricted, and mechanistically simple

One possible condition is gastroparesis, where the stomach empties very slowly

You would start retatrutide at the lowest dose and gradually increase it (called titration), regardless of what dose of tirzepatide you were on

Educating the patient about these variations helps them understand the potential differences in insulin action and adjust their self-management strategies accordingly