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According to a study presented at the 2025 Society of Hematologic Oncology (SOHO) meeting, patients with PV who received GLP-1 therapy experienced : - *Reduced All-Cause Mortality*: Lower odds of death from any cause - *Lower Rates of Myelofibrosis Progression*: Decreased risk of progression to myelofibrosis, a condition where scar tissue builds up in the bone marrow - *Decreased Venous Thromboembolism (VTE)*: Fewer blood clots - *Fewer Hospitalizations*: Reduced need for hospitalization - *Reduced Risk of Acute Kidney Injury and Ischemic Stroke*: Lower risk of kidney damage and stroke

When you have plenty of vitamin C in your system, it handles the initial wave of oxidative stress

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Through a transcriptional/translational feedback loop, the heterodimer BMAL1/CLOCK activates the heterodimer Per/Cry expression that suppresses the transcription of BMAL1 and CLOCK (5961)