semaglutide and alcohol use reduces binge-like drinking in mice. (A) Semaglutide for weight loss was

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The GLP-1 receptor belongs to the G protein-coupled receptor (GPCR) B family, consisting of seven transmembrane helices (TMH) interconnected by intracellular loops, with a C-terminal intracellular domain and a large (~120 amino acid) N-terminal extracellular domain (ECD) (65)