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(PubMed) Petronek MS, Monga V, Bodeker KL, et al

Therapeutically, this raises two complementary possibilities: (1) SQOR-high tumors may exhibit enhanced mitochondrial ferroptosis resistance through maintained CoQ 10 H 2 and sulfur-based RTAs and (2) tumors with altered sulfur/selenium metabolism may reveal synthetic vulnerabilities when SQOR-linked defense is impaired

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Apr 16 2020;9(4)doi:10.3390/cells9040990