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These results position Epitalon as a potential candidate for stabilizing cholinergic tone, a critical early disruption in age-related cognitive decline, and for addressing cognitive disorders associated with cholinergic deficiency and amyloid metabolism

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EPCs contribute to postnatal vasculogenesis, and are recruited from the bone marrow to sites of injury via growth factors, cytokines and hypoxia-related signaling pathways, where they differentiate into mature endothelial cells and incorporate themselves into sites of active neovascularization [41, 51]

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