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The research emphasis differs from BPC-157: where BPC-157 work often centers on vascular and cytoprotective signaling, TB-500 work often centers on the cytoskeleton and cell motility

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Structurally, BPC-157 is notable for a proline-rich backbone (five Pro residues, including a Pro-Pro-Pro triad) together with two acidic Asp residues, one Glu, a single basic Lys, and a hydrophobic C-terminal Leu-Val motif, giving the sequence a distinctive residue distribution relevant to secondary-structure modeling, chromatographic behavior, and mass-spectral fragmentation patterns

HandLEGrayKJDicksonSHSimpkinsDARayDWKonkelJEet al