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While chronically low levels of glutathione can lead to cell damage and chronic disease, increased levels might prevent illnesses and upping production is often the treatment for many chronic diseases

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Prospective studies are advantageous over retrospective studies since blood samples to measure IGF1 levels are collected before the clinical diagnosis of cancer and hence reverse causation (i.e., effects of an undiagnosed cancer on levels of IGF1) is less likely to play a role 50

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Moreover, GST isozymes (Alpha, Mu, and Pi) are frequently over-expressed in neoplastic tissues and have been considered as an important marker for a number of tumors such as lung, ovarian, breast, and gastric carcinoma [2, 3]

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