In some embodiments, administration of a formulation or composition or device described herein in combination with an otic intervention (e.g., an intratympanic injection, a stapedectomy, a medical device implant, or a cell-based transplant) delays or prevents collateral damage to auris structures, e.g., irritation, cell damage, cell death, osteoneogenesis, and/or further neuronal degeneration, caused by the external otic intervention (e.g., installation of an external device and/or cells in the ear)
Epinephrine levels were detected using the Mouse epinephrine kit (cat
The induction of LC3II/I observed at 6 h may be ascribed to an AMPK inhibition-independent downregulation of Akt/mTOR pathway, as previously reported
Adult: Take 1 Capsule or as directed by your healthcare professional