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King and Macrae 2015

Recently, a hybrid model (cuprizone autoimmune encephalitis or CAE) combining the myelin-toxic effects of cuprizone (Zirngibl et al., 2022) together with an immune stimulation identical to EAE but without extrinsic myelin peptides, provided proof-of-principle for the notion that a primary biochemical dysmyelination can result in a very typical inflammatory demyelinating white matter lesion in an immune-stimulated host (Caprariello et al., 2018)

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If you missed your injection by a few days, take it as soon as you rememberdelaying longer than 23 days from your scheduled dose window may reduce efficacy slightly, but resuming promptly restores effectiveness within 23 days